Pneumologisches Forschungsinstitut an der LungenClinic Grosshansdorf GmbH

2.5 | PUBLIKATIONEN


Die Ergebnisse unserer Forschungsaktivitäten publizieren wir in internationalen Fachzeitschriften und auf wissenschaftlichen Kongressen der amerikanischen und europäischen Pneumologenvereinigungen. Datenbank-gelistete Publikationen finden Sie hier unter PubMed

Eine Liste der seit 2014 publizierten Kongressbeiträge ist im Folgenden aufgeführt. Eine vollständige Lister aller publizierten Kongressbeiträge kann jederzeit unter angefordert werden.

1. Kahnert K, Alter P, Young D, Lucke T, Heinrich J, Huber RM, Behr J, Wacker M, Biertz F, Watz H, Bals R, Welte T, Wirth H, Herth FJF, Vestbo J, Wouters EFM, Vogelmeier C, Jörres RA (2018) The revised GOLD 2017 COPD categorization in relation to comorbidities. Pneumologie 72; S102

2. Facius A, Bagul N, Gardiner P, Watz H (2018) Pharmacokinetics and pharmacodynamics of a 4-week up-titration regimen of roflumilast in the optimize study. Pneumologie 72; S92

3. Wiest HG, Ferguson GT, Watz H, Maltais F, Grönke L, Voss F, Buhl R (2018) The impact of grouping patients by the 2017 GOLD COPD strategy on response to therapy: post hoc results from the TONADO tiotropium+Olodaterol trials. Pneumologie 72; S91

4. Seiler F, Trudzinski FC, Fähndrich S, Watz H, Jörres RA, Koch A, Welte T, Vogelmeier C, Biertz F, Bals R (2018) Definition und Charakterisierung eines inflammatorischen Phänotyps bei Patienten mit COPD-Ergebnisse aus der nationale COPD-Kohorte COSYCONET. Pneumologie 72; S87

5. Lutter J, Wacker M, Jörres RA, Schulz H, Karrasch S, Karch A, Leidl R, Watz H, Vogelmeier C, Holle R (2018) Welche Faktoren prädizieren eine Verschlechterung des gesundheitsbezogenen Lebensqualität bei COPD? Erst längsschnittliche Ergebnisse der COSYCONET COP-Kohorte. Pneumologie 72; S83

6. Trudzinski FC, Alqudrah M, Seiler F, Biertz F, Vogelmeier C, Welte T, Watz H, Fähndrich S, Jörres RA (2018) Bals R Patienten mit COPD und chronischer Niereninsuffizienz, Daten aus der COPD Kohorte COSYCONET. Pneumologie 72; S77

7. Alter P, Watz H, Kahnert K, Rabe KF, Jung P, Biertz F, Graf J, Bals R, Vogelmeier C, Jörres RA (2018) Einflüsse von Obstruktion und Überblähung bei OCPD auf die elektrische Herzachsen von P-Welle, QRS-Komplex und T-Welle im EKG. Pneumologie 72; S73

8. Bahmer T, Watz H, Pedersen F, Kirsten AM, Waschki B, Von Mutius E, Hansen G, Kopp MV, Rabe KF, Fuchs O, Weckmann M, Koenig IR, Thiele D, Chaker A, Jackwerth CA, Schmidt-Weber CB, Zissler UM (2018) Nasal Cytokine Patterns in Patients with Asthma. Am J Respir Crit Care Med 2018;197:A7198

9. Alter P, Watz H, Kahnert K, Rabe KF, Biertz F, Fischer R, Jung P, Graf J, Bals R, Vogelmeier CF, Jörres RA (2018) Effects of Airway Obstruction and Hyperinflation on Electrocardiographic Axes in COPD. Am J Respir Crit Care Med 2018;197:A4989

10. Pedersen F, Zissler U, Watz H, Rabe KF, Hohlfeld JM, Holz O (2018) A Comprehensive Way to Rate Sputum Quality in Clinical Trials. Am J Respir Crit Care Med 2018;197:A4769

11. Sethi S, Kerwin EM, Watz H, Ferguson GT, Mroz R, Segarra R, Molins E, Jarreta D, Garcia Gil E (2018) AMPLIFY: A Randomized, Phase III Study Evaluating the Efficacy and Safety of Aclidinium/Formoterol Versus Monotherapy in Patients with COPD. Am J Respir Crit Care Med 2018;197:A4241

12. Trudzinski FC, Alqudrah M, Zewinger S, Danilo F, Seiler F, Biertz F, Koch A, Vogelmeier C, Welte T, Watz H, Faehndrich S, Jorres R, Bals R (2018) Chronic Kidney Disease Is an Independent Risk Factor for Reduced Physical Activity and Exercise Capacity in COPD Patients, Data from the German Cosyconet Cohort. Am J Respir Crit Care Med;197: A1711
13. Waschki B, Alter P, Zeller T, Magnussen C, Twerenbold R, Blankenberg S,Omlor A, Herr C, Rabe K, Welte T, Jörres RA, Vogelmeier C, Bals R, Watz H (2018) Late Breaking Abstract - High-sensitivity troponin I predicts all-cause mortality in stable COPD in the COSYCONET cohort. Eur Respir J 52: Suppl 62, OA2138.

14. Alter P, Watz H, Kahnert K, Rabe KF, Biertz F, Fischer R, Jung P, Graf J, Bals R, Vogelmeier CF, Jorres RA (2018) Influences of obstruction and hyperinflation on electrocardiographic P wave, QRS and T wave axis in COPD. Eur Respir J 52: Suppl 62, PA3348

15. Ferguson GT, Shaikh A, Tetzlaff K, Mueller A, Watz H (2018) Effect of ICS withdrawal on COPD exacerbations in patients on triple therapy at baseline. Eur Respir J 52: Suppl 62, PA4379

16. Seiler F, Trudzinski FC, Fähndrich S, Watz H, Jörres RA, Koch A, Welte T, Vogelmeier CF, Biertz F, Bals R (2018) Definition and characterization of an inflammatory phenotype in patients with COPD - results from the COSYCONET study. Eur Respir J 52: Suppl 62, PA4097

17. Sethi S, Kerwin E, Watz H, Ferguson GT, Mroz R, Segarra R, Molins E, Jarreta D, Garcia-Gil E (2018) AMPLIFY: efficacy of aclidinium vs tiotropium in COPD. Eur Respir J 52: Suppl 62, PA4393

18. Kahnert K, Alter P, Welte T, Huber RM, Behr J, Biertz F, Watz H, Bals R, Vogelmeier CF, Jörres RA (2018) Uric acid, lung function, physical capacity and exacerbation frequency in patients with COPD: a multi-dimensional approach. Eur Respir J 52: Suppl 62, PA1178

19. Watz H, Magnussen H, Rodriguez-Roisin R, Tetzlaff K, Haensel M, Mueller A, Vogelmeier C (2018) ICS withdrawal and exacerbation risk by GOLD 2017 Report: post hoc analysis of the WISDOM trial. Eur Respir J 52: Suppl 62, OA289

20. Wacker ME, Jörres RA, Schulz H, Karrasch S, Koch A, Leidl R, Watz H, Vogelmeier C, Holle R (2017) What predicts a deterioration of generic and disease-specific health-related quality of life in COPD? First longitudinal results of the COSYCONET cohort. European Respiratory Society Congress, PA4970

21. Garcia Aymerich J, Watz H, Beeh Km, Paggiaro P, Moya M, Notari M, Jarreta D, Garcia Gil E, Troosters T (2017) Use of the Daily PROactive instrument to evaluate physical activity in patients with COPD: results from ACTIVATE. European Respiratory Society Congress, PA4964

22. Derom E, Watz H, Grönke L, Voss F, Buhl R (2017) Determining SGRQ and TDI responder rates across the duration of clinical trials: Results from tiotropium + olodaterol in COPD. European Respiratory Society Congress, PA4958

23. Miller B, Lazaar A, Tabberer M, Yonchuk J, Collins D, Leidy N, Ambery C, Bloomer J, Watz H, Tal-Singer R (2017) Danirixin (GSK1325756) improves respiratory symptoms and health status in mild to moderate COPD – results of a 1 year first time in patient study. European Respiratory Society Congress, PA3885

24. Ferguson GT, Watz H, Maltais F, Grönke L, Voss F, Buhl R (2017) The impact of grouping patients by the 2017 GOLD COPD strategy on response to therapy: post hoc results from the TONADO tiotropium+olodaterol trials. European Respiratory Society Congress, PA3634

25. Greulich T, Hohlfeld JM, Klemmer A, Homburg U, Renz J, Garn H, Renz H, Neuser P, Harnisch S, Schade-Brittinger C, Kirsten A, Pedersen F, Watz H, Lueer K, Vogelmeier CF (2017) A GATA3-specific DNAzyme attenuates sputum eosinophilia in COPD patients with eosinophilic airway inflammation. European Respiratory Society Congress, OA2896

26. Bahmer T, Watz H, Develaska M, Waschki B, Rabe KF, Magnussen H, Kirsten D, Kirsten AM (2017) Physical activity in patients with sarcoidosis. European Respiratory Society Congress, PA2261

27. Alter P, Jörres RA, Watz H, Welte T, Gläser S, Schulz H, Bals R, Biertz F, Wouters E, Vestbo J, Young D, Vogelmeier C (2017) Left ventricular volume and wall stress are linked to lung function impairment in COPD. European Respiratory Society Congress, OA1960

28. Kahnert K, Lucke T, Huber RM, Behr J, Biertz F, Vogt A, Watz H, Alter P, Fähndrich S, Bals R, Holle R, Karrasch S, Söhler S, Wacker M, Ficker JH, Parhofer K, Vogelmeier C, Jörres RA (2017) Relationship of hyperlipidemia to comorbidities and lung function in COPD: results of the COSYCONET cohort. European Respiratory Society Congress, OA1787

29. Watz H, Troosters T, Beeh KM, Garcia-Aymerich J, Paggiaro P, Molins E, Notari M, Jarreta D, Garcia Gil E(2017) ACTIVATE: effect of aclidinium/formoterol on physical activity in patients with COPD. European Respiratory Society Congress, PA687

30. Trudzinski F, Alqudrah M, Seiler F, Biertz F, Koch A, Vogelmeier C, Welte T, Watz H, Fähndrich S, Bals R, Jörres RA (2017) The presence and impact of chronic kidney disease in COPD patients, data from the German COSYCONET cohort. European Respiratory Society Congress, PA701

31. Demeyer H, Waschki B, Polkey M, Furlanetto K, Donaire-Gonzalez D, Anto JM, Pitta F, Hopkinson N, Troosters T, Watz H, Garcia-Aymerich j (2017) The survival effect of physical activity in patients with COPD: every step counts. European Respiratory Society Congress, OA512

32. Seiler F, Trudzinski FC, Alquadrah M, Fähndrich S, Watz H, Jörres RA, Koch A, Welte T, Vogelmeier CF, Biertz F, Bals R (2017) Association of inflammatory biomarkers with comorbidity in chronic obstructive pulmonary disease – results from the COSYCONET cohort. European Respiratory Society Congress, PA392

33. Bahmer T, Kirsten A, Waschki B, Rabe KF, Magnussen H, Kirsten D, Gramm M, Hummler S, Brunnemer E, Kreuter M, Watz H (2017) Prognosis and longitudinal changes of physical activity in Idiopathic Pulmonary Fibrosis. Am J Respir Crit Care Med 195: A7006

34. Kahnert K, Lucke T, Biertz F, Lechner A, Alter P, Bals R, Watz H, Behr J, Holle R, Huber RM, Karrasch S, Stubbe B, Wacker M, Sohler S, Wouters EFM, Vogelmeier C, Jorres R (2017) Transfer factor for carbon monoxide in patients with COPD and diabetes: results from the German COSYCONET cohort. Am J Respir Crit Care Med 195: A6492

35. Pedersen F, Waschki B, Marwitz S, Goldmann T, Kirsten A, Rabe KF, Malmgren A, Richter K, Uddin M, Watz H (2017) The chemokine receptor CXCR2 regulates formation of neutrophil extracellular traps in COPD patients. Am J Respir Crit Care Med 195: A6293

36. Janciauskiene S, Watz H, Holz O, Magnussen H, Olejnicka B, Welte T, Rabe KF, Waschki B (2017) Plasminogen activator inhibitor-1 is elevated in patients with COPD independently of metabolic and cardiosvascular function. Am J Respir Crit Care Med 195: A3627

37. Maleki-Yazdi MR, Watz H, Bothner U, Tetzlaff K, Trampisch M, McGarvey L (2017) A comprehensive assessment of the safety profile of Olodaterol in the Respimat® device versus Formoterol for maintenance treatment of COPD. Am J Respir Crit Care Med 195: A3597

38. Watz H, Troosters T, Beeh KM, Garcia Aymerich J, Paggiaro P, Molins E, Notari M, Jarreta D, Garcia Gil E (2017) Effect of aclidinium/formoterol on lung hyperinflation, exercise capacity and physical activity in patients with COPD. Am J Respir Crit Care Med 195: A3593

39. Hessel EM, Hamblin JN, Begg M, Wilson R, Dunsire L, Sriskantharajah S, Montembault M, Leemereise C, Galinanes-Garcia L, Watz H, Kirsten A, Fuhr R, Cahn A (2017) Safety, pharmacokinetics and dose-response characteristics of GSK2269557, an inhaled PI13Kδ inhibitor under development for the treatment of COPD. Am J Respir Crit Care Med 195: A7570

40. Rabe K, Saetta M, Watz H, Baraldo S, Hanauer G, Göhring UM, Delgadillo J, Roman J, Alagappan V (2017) Reduction in airway eosinophils in patients with COPD treated with Roflumilast for 16 weeks: a double-blind, parallel-group, randomized, placebo-controlled biopsy trial. Am J Respir Crit Care Med 195: A7569

41. Facius A, Bagul N, Gardiner P, Watz H (2017) Pharmacokinetics of a 4-week up-titration regimen of Roflumilast in the OPTIMIZE study. Am J Respir Crit Care Med 195: A1337
42. Vogelmeier C, Fabbri LM, Bell S, Tetzlaff K, Magnussen H, Watz H (2017) Identification of factors associated with exacerbation risk in severe COPD: multivariate analysis of the WISDOM study. Pneumologie 71: V154

43. Calverley PMA, Tetzlaff K, Vogelmeier C, Fabbri LM, Magnussen H, Wouters EFM, Disse B, Finnigan H, Asijee GM, Watz H (2017) Evaluating blood eosinophils and exacerbation history to predict ICS response in COPD. Pneumologie 71: P251

44. Richeldi, L, Selman M, Kirsten AM, Wuyts WA, Bernoids K, Stowasser S, Quaresma M, Costabel U (2016) Long-term efficacy and safety of nintedanib in patients with idiopathic pulmonary fibrosis (IPF): results from the TOMORROW trial and its open-label extension, ICLAF 2016 JQM 109 suppl1

45. Alter P, Watz H, Welte T, Gläser S, Schulz H, Bals R, Söhler S, Karch A, Vogelmeier C, Jörres RA (2016) COPD influences on left heart wall stress — An analysis of the COSYCONET cohort. Eur Respir J;48:Suppl.60 PA5029

46. Watz H, Kirsten A, Pedersen F, Goldmann T, Stellmacher F, Uddin M, Larsson B, Böttcher G, Malmgren A, Kraan M, Rabe KF (2016) Neutrophils in bronchial mucosa, sputum and blood after administration of the CXCR2-antagonist AZD5069 - An explorative study in neutrophilic asthma. Eur Respir J;48:Suppl.60 PA4892

47. Watz H, Pedersen F, Kirsten A, Nagelschmitz J, Bandel TJ, Schwers S, Rabe KF (2016) Safety and tolerability of the NE inhibitor BAY 85-8501 in patients with non-CF bronchiectasis. Eur Respir J;48:Suppl.60 PA4088

48. Magnussen H, Arzt M, Andreas S, Plate T, Ribera A, Seoane B, Watz H, Kirsten AM (2016) The effect of aclidinium bromide 400 μg on sleep quality in COPD: A pilot study. Eur Respir J;48:Suppl.60 PA4051

49. Vogelmeier C, Fabbri LM, Bell S, Tetzlaff, K, Magnussen, Watz H (2016).Identification of factors associated with exacerbation risk in severe COPD: Multivariate analysis of the WISDOM study. Eur Respir J;48:Suppl.60 PA302

50. Fähndrich S, Biertz F, Watz H, Welte T, Karch A, Koch A, Kauczor HU, Jörres RA, Vogelmeier C, Bals R (2016) Differences in the disease phenotype and comorbidities between patients with COPD and alpha-1-antitrypsin deficiency - An analysis of the COSYCONET cohort. Eur Respir J;48:Suppl.60 PA3111

51. Waschki B, Kirsten A, Holz O, Meyer T, Lichtinghagen R, Rabe KF, Magnussen H, Welte T, Watz H, Janciauskiene S (2016) Association of angiopoietin-like protein 4 with cardiovascular function in patients with COPD. Eur Respir J;48:Suppl.60 OA3004

52. Calverley MA, Tetzlaff K, Vogelmeier C, Fabbri LM, Magnussen H, Wouters E, Disse B, Finnigan H, Asijee GM, Watz H (2106) LATE-BREAKING ABSTRACT: Evaluating blood eosinophils and exacerbation history to predict ICS response in COPD. Eur Respir J;48:Suppl.60 OA1973

53. Bahmer T, Kirsten A, Schatz F, Herzmann C, Waschki B, Rabe KF, Watz H (2016) Physical activity in patients with asthma. Eur Respir J;48:Suppl.60 PA1578

54. Karrasch S, Schäfer J, Kiehl G, Lucke T, Sußmann M, Luzak A, Ochmann U, Nowak D, Jörres RA, Vogelmeier C, Watz H, Schulz H, COSYCONET Study Group (2016) Comparison of physical activity measures assessed by two different accelerometers in COPD patients. Eur Respir J;48:Suppl.60 PA1154

55. Wacker ME, Jörres RA, Karch A, Wilke S, Heinrich J, Karrasch S, Koch A, Schulz H, Watz H, Leidl R, Vogelmeier C, Holle R (2016). Can disease-specific questionnaires describe the effect of comorbidities on health-related quality of life in patients with COPD? A comparison of disease-specific and generic questionnaires in the COSYCONET cohort. Eur Respir J;48:Suppl.60 PA1150

56. Miller B, Tal-Singer R, Lazaar A, Leidy N, Watz H, Collins D, Yonchuk J, Tabberer M (2016). Assessing symptoms in COPD: Use of the E-RS daily digital diary in early drug development. Eur Respir J;48:Suppl.60 PA1047

57. Watz H, Bagul N, Nip K, Sun K, Goehring U, Calverley P, Rabe KF (2016). Tolerability of different dosing regimens of roflumilast in severe COPD (OPTIMIZE). Eur Respir J;48:Suppl.60 PA308

58. Vogelmeier C, Fabbri LM, Bell S, Tetzlaff, K, Magnussen, Watz H (2016).Identification of factors associated with exacerbation risk in severe COPD: Multivariate analysis of the WISDOM study. Eur Respir J;48:Suppl.60 PA302

59. Beier J, Mroz R, Kirsten AM, Chuecos F, Garcia GilI E (2016) Improvement in lung function and symptom control with aclidinium bromide versus tiotropium and placebo in symptomatic patients with COPD: post-hoc analysis of a Phase IIIb study Am J Respir Crit Care Med 2016A: 6817

60. Houben-Wilke S, Jorres RA, Bals R, Franssen FME, Glaeser S, Holle R, Karch A, Koch A, Magnussen H, Obst A, Schulz H, Spruit MA, Wacker ME, Welte T, Wouters EFM, Vogelmeier C, Watz H (2016) Peripheral artery disease and its clinical relevance in patients with Chronic Obstructive Pulmonary Disease in the COPD and Systemic Consequences-Comorbidities Network Study. Am J Respir Crit Care Med 195: XX

61. Magnussen H, Arzt M, Andreas S, Plate T, Ribera A, Seoane B, Watz H, Kirsten AM (2016) The effect of aclidinium bromide 400 µg on lung function, sleep quality and physical activity in patients with Chronic Obstructive Pulmonary Disease: Results of a phase IV pilot study. Am J Respir Crit Care Med: A6820

62. Watz H, Magnussen H, Tetzlaff K, Gronke L, Finnigang H, Calverley PM (2016) Is blood eosinophil count a predictor of disease worsening after ICS withdrawal? Am J Respir Crit Care Med 2016: A6234

63. Waschki B, Kirsten AM, Holz O, Meyer T, Lichtinghagen R, Rabe KF, Magnussen H, Welte T, Watz H, Janciauskiene S (2016) α 1-Antitrypsin (A1AT) serum levels as marker of systemic inflammation in non-A1AT-deficient patients with COPD. Am J Respir Crit Care Med 2016: A3488

64. Alter P, Watz H, Welte T, Glaser S, Schulz H, Bals R, Sohler S, Karch A, Vogelmeier C, Jörres RA (2016) Spirometric and bodyplethysmographiclLung function is associated with echocardiography-derived ventricular wall stress in COPD. Am J Respir Crit Care Med 2016: A2988

65. Richeldi, L, Selman M, Kirsten AM, Wuyts WA, Bernoids K, Stowasser S, Quaresma M, Costabel U (2016) Long-term efficacy and safety of nintedanib in patients with idiopathic pulmonary fibrosis (IPF): results from the TOMORROW trial and its open-label extension, ICLAF 2016 JQM 109 suppl1
DOI:http://dx.doi.org/10.1093/qjmed/hcw127.006

66. Vogelmeier C, Paggiaro PL, Dorca J, Sliwinski P, Mallet M, Kirsten AM, Seoane B, Segarra RM, Leselbaum A, GarciaGil E (2016) Efficacy of aclidinium/formoterol fixed-dose combination versus salmeterol/fluticasone in COPD. Pneumologie 70: P364

67. Bahmer T, Watz H, Waschki B, Gramm M, Magnussen H, Rabe KF, Wirtz H, Kirsten D, Kirsten AM (2016) Körperliche Aktivität und der Einfluss von Atemwegsobstruktion, Gesundheitsstatus und Fatigue bei Patienten mit Lymphangioleiomyomatose. Pneumologie 70: P557

68. Watz H, Mailänder C, Kirsten AM (2016) Überlegenheit von Glycopyrronium im Vergleich zu Tiotropium in der früh-einsetzenden Bronchodilatation von Patienten mit moderater bis schwerer COPD - Die FAST Studie. Pneumologie 70: P197

69. Watz H, Ferguson GT, Grönke L, Voss F, Abrahams, R, Buhl R (2016) Inhaled corticosteroid plus long-acting beta2-agonist therapy is overused in the treatment of patients with Chronic Obstructive Pulmonary Disease: Post hoc analyses of two 1-year studies. Pneumologie 70: P247

70. Watz H, Kalberg C, Brooks J, Worsley S, Harris S, Zvarich M, Church A (2016) Wirkungseintritt von Umeclidinium/Vilanterol im Vergleich zu anderen Erhaltungstherapien bei Patienten mit COPD. 57. Pneumologie 70: P321

71. Watz H, Mailänder C, Kirsten AM (2016) Effekte von Indacaterol/Glycopyrronium auf Lungenfunktion und die gemessene körperliche Aktivität von Patienten mit moderater bis schwerer COPD. 57. Pneumologie 70:P205

72. Watz H, Derom E, Korn S, Hamilton A, Amatto VC, Zhao Y, Maltais F (2016) Efficacy of tiotropium and olodaterol fixed-dose combination in patients with COPD on beta-blockers. 57. Pneumologie 70: P426

73. Watz H, Ferguson GT, Grönke L, Voss F, Abrahams R, Buhl R (2015) Inhaled corticosteroid plus long-acting ß2-agonist therapy is overused in the treatment of patients with chronic obstructive pulmonary disease: post hoc analyses of two 1-year studies. Thorax 70:A137

74. Watz H, Mailänder C, Kirsten A (2015) Effects of indacaterol/glycopyrronium on lung function and physical activity in patients with moderate to severe COPD. Thorax 70: A146

75. Watz H, Mailänder C, Kirsten AM (2015) Superiority of glycopyrronium versus tiotropium in early onset of bronchodilation in patients with moderate to severe COPD- the FAST study. Thorax 70: A140

76. Watz H, Magnussen H, Rodriguez-Roisin, R, Wouters E, Disse B, Tetzlaff K, Finnigan H, Calverley P (2015) Subgroup Analyses of Lung-Function Change from the WISDOM Study. Chest 148:755A

77. Kirsten AM, Watz H, Kirsten D (2015) Lymphangioleiomyomatose und Pneumothoraxrisiko beim Fliegen Pneumologie 69: P488

78. Magnussen H Chanez P, Dahl R, Decramer MLA, Disse B, FinniganH, Kirsten AM, Rodriguez-Roisin R, Tetzlaff K, Towse L, Watz H, Wouters E, Calverley P (2015) The impact of stepwise withdrawal of inhaled corticosteroids on exacerbations in COPD patients receiving dual bronchodilation: WISDOM study Pneumologie 69: P75

79. Watz H, Calverley P, Chanez P, Dahl R, Decramer MLA, Disse B, Finnigan H, Kirsten AM, Rodriguez-Roisin R, Tetzlaff K, Towse L, Wouters E, Magnussen H (2015) The impact of stepwise withdrawal of inhaled corticosteroids on lung function in COPD patients receiving dual bronchodilation: WISDOM study Pneumologie 69: P67

80. Pedersen F, Marwitz S, Goldmann T, Kirsten A, Magnussen H, Rabe KF, Uddin M, Watz H (2015) Enhanced neutrophil extracellular trap (NET) formation in sputum of stable COPD patients. Eur Respir J 46 Suppl. 59, PA379

81. Alter P, Karch A, Watz H, Koch A, Welte T, Schulz H, Jörres R, Vogelmeier C (2015) COPD is associated with left ventricular size and function: Results from COSYCONET. Eur Respir J 46 Suppl. 59, PA613

82. Watz H, Magnussen H, Kirsten A, Tetzlaff K, Finnigan H, Disse B, Batemann E (2015) Lung Function change and exacerbations in patients with COPD in the WISDOM study. Eur Respir J 46 Suppl. 59, PA1019

83. Wilke S, Bals R, Franssen F, Karch A, Koch A, Schulz H, Spruit M, Welte T, Wouters E, Jörres R, Vogelmeier C, Watz H (2015) Impact of peripheral artery disease on functional capacity in patients with COPD: Results of the COSYCONET study. Eur Respir J 46 Suppl. 59, PA2069

84. Waschki B, Kirsten A, Holz O, Müller K-C, Schaper M, Sack A-L, Meyer T, Rabe K, Magnussen H, Watz H (2015) The role of sustained inactivity in the progression of exercise intolerance and muscle depletion in COPD. Eur Respir J 46 Suppl. 59, PA3550

85. Esser R W, Stoeckel M C, Kirsten A, Watz H, Lehmann K, Taube K, Büchel C, Magnussen H, Leupoldt Von A (2015) Neural correlates of dyspnea in COPD. Eur Respir J 46 Suppl. 59, OA4954

86. Martinez F J, Calverley P M A, Goehring U-M, Hodge R, Fabbri L M, Rabe K F (2015) Effect of roflumilast on exacerbations in patients with severe COPD and a prior history of hospitalization taking combination therapy. Eur Respir J 46 Suppl. 59, OA482

87. Annoni R, Couceiro L, Barbosa S, Lancas T, Battaglia S, Dolhnikoff M, Hiemstra P, Ster P, Rabe K, Mauad T (2015). Versican and collagen-III expression in bronchial and pulmonary muscular arteries in COPD patients. Eur Respir J 46 Suppl. 59, PA2446

88. Vogelmeier C, Paggiaro PL, Dorca J, Sliwinski P, Mallet M, Kirsten A-M, Seoane B, Segarra RM, Leselbaum A, Garcia Gil E (2015) Efficacy of aclidinium/formoterol fixed-dose combination versus salmeterol/fluticasone in COPD. Eur Respir J 46 Suppl. 59, PA2960

89. Rabe K, Martinez F, Rodriguez-Roisin R, Fabbri L M, Ferguson G T, Jones P, Rennard S, Golden M, Darken P, Orevillo C, Fischer T, Reisner C (2015) PT003, a novel co-suspension MDI glycopyrronium/formoterol fixed-dose combination is superior to monocomponents in patients with COPD. Eur Respir J 46 Suppl. 59, PA4363

90. Jörres R A, Biertz F, Vogel C, Kauczor H-U, Biederer J, Jobst B, Heinrich J, Koch A, Watz H, Welte T, Vogelmeier C (2015) Chest CT scans obtained in multicentre clinical routine assessments are sufficient to develop a prediction function for emphysema from lung function. Eur Respir J 46 Suppl. 59, OA4986

91. Wacker M E, Wilke S, Karch A, Schulz H, Watz H, Jörres R A, Vogelmeier C, Holle R (2015) Assessing health-related quality of life in COPD: A comparison between one generic and two disease-specific instruments. Eur Respir J 46 Suppl. 59,PA5074

92. Watz H, Mailaender C, Kirsten AM (2015) Superiority of Glycopyrronium versus Tiotropium in Early Onset of Bronchodilation in Patients with Moderate to Severe COPD - The FAST Study. Am J Respir Crit Care Med 191:A5763

93. Bateman ED, Rodriguez-Roisin R, Calverley PM, Tetzlaff K, Disse B, Finnigan H, Magnussen H, Watz H (2015) Withdrawal of Inhaled Corticosteroids and Exacerbations of COPD: The WISDOM Phenotyping Substudy. Am J Respir Crit Care Med 191:A3979

94. Jorres RA, Biertz F, Vogel C, Kauczor HU, Biederer J, Jobst B, Heinrich J, Koch A, Watz H, Welte T, Vogelmeier C (2015) Prediction of Emphysema from Lung Function Parameters and Chest CT Scans Obtained in Clinical Routine: Results of the German COSYCONET Study. Am J Respir Crit Care Med 191:A2257

95. Wilke S, Watz H, Bals R, Franssen F, Holle R, Karch A, Koch A, Schulz H, Spruit, MA, Wacker ME, Welte T, Wouters EFM, Jorres RA, Vogelmeier C (2015) Impact of Peripheral Artery Disease on Functional Capacity and Health Status in Patients with Chronic Obstructive Pulmonary Disease: Results of the COSYCONET Study. Am J Respir Crit Care Med 191:A6204

96. Watz H, Wilke S, Bals R, Karch A, Koch A, Schulz H, Welte T, Vogelmeier C, Jorres RA (2015) Prevalence of Peripheral Artery Disease in Patients with Chronic Obstructive Pulmonary Disease: Results of the COSYCONET Study. Am J Respir Crit Care Med 191:A5710

97. Magnussen H, Bateman ED, Watz H, Kirsten A, Tetzlaff K, Disse B, Finnigan H, Rodriguez-Roisin R, Calverley PM (2015) High Level of Agreement Between Home-Based and In-Clinic Spirometry Results in the WISDOM COPD Study. Am J Respir Crit Care Med 191:A5806

98. Watz H, Bateman ED, Magnussen H, Kirsten A, Tetzlaff K, Disse B, Finnigan H, Calverley PM, Rodriguez-Roisin R (2015) Stepwise Withdrawal of Inhaled Corticosteroids in COPD Patients Receiving Dual Bronchodilators: Lung Function Reduction in the WISDOM Study. Am J Respir Crit Care Med 191:A3641

99. Watz H, Ferguson G, Gronke L, Vob F, Abrahams R, Buhl R (2015) Inhaled Corticosteroid Plus Long-Acting β2-Agonist Therapy is Overused in the Treatment of Patients with Chronic Obstructive Pulmonary Disease: Post Hoc Analyses of Two 1-Year Studies. Am J Respir Crit Care Med 191:A5784

100. Vogelmeier C, Paggiaro PL, Dorca J, Sliwinski P, Mallet M, Kirsten AM, Seoane B, Segarra RM, Leselbaum A, Garcia Gil E (2015) The Efficacy and Safety of Aclidinium/Formoterol Fixed-Dose Combination Compared with Salmeterol/Fluticasone in Patients with COPD: Results from a Phase III Study. Am J Respir Crit Care Med 191: A3974

101. O'Donnell D, Casaburi, R, De Sousa D, Xue W, Frith P, Hamilton A, Kirsten A, Maltais F (2015) Effects of 6 Weeks' Treatment with Once-Daily Tiotropium and Olodaterol Fixed-Dose Combination on Inspiratory Capacity and Exercise Endurance in Patients with COPD: The MORACTO™ Studies. Am J Respir Crit Care Med 191: A3972

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103. Kirsten AM, Richard A, Tanase A-M, Weihua C, Hosoe M, Hederer B (2015) Wirksamkeit und Sicherheit von Indacaterol/Mometason verglichen mit Salmeterol/Fluticason bei Patienten mit mäßiger bis schwerer COPD. Pneumologie 69: P55

104. Kirsten AM, Richeldi L, Roman J, LeMaulf F, Hallmann C, Stowasser S, Lasky JA (2015) Pooled analysis of mortality data from the TOMORROW and INPULSIS™ trials of nintedanib in idiopathic pulmonary fibrosis (IPF) Pneumologie 69: P24

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106. Kirsten AM, Richard A, Tanase AM, Weihua C, Hosoe M, Hederer B (2014) Efficacy and safety of once-daily indacaterol/mometasone compared with twice-daily salmeterol/fluticasone in patients with moderate to very severe COPD. Thorax 69: P P251

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109. Holz O, Müller M, Ignatenko S, Kappeler D, Buhl R, Beeh KM, Kornmann O, Kirsten A, Homburg U, Garn H, Krug N, Hohlfeld JM (2014) Effect Of Sample Processing On The Analysis Of IL4, IL5, And IL13 In Sputum Supernatants Am J Respir Crit Care Med 189: A 4255

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112. Seehase S, Watz H, Kugler C, Vollmer E, Goldmann T (2014) Surfactant protein expression at various COPD Gold stages. Eur Respir J 44: Suppl. 58, 3994

113. Watz H, Nagelschmitz J, Pedersen F, Ringshausen FC, Kirsten A, Magnussen H, Rabe KF, Welte T, Rademacher J, Rentzsch C, Schumann C, Zubov D, Schäfer S, Schwers S (2014) Conduct of a biomarker study in bronchiectasis patients: Correlation of neutrophil elastase activity and inflammatory load in induced sputum. Eur Respir J 44: Suppl. 58, 2049

114. Nagelschmitz J, Kaufel D, Stephan S, von Nussbaum F, Delbeck V, Lustig K, Bandel T, Watz H (2014) The novel elastase inhibitor BAY 85-8501 provides a new approach in the treatment of pulmonary diseases. Eur Respir J 44: Suppl. 58, 3416

115. Watz H, Calverley P, Chanez P, Dahl R, Decramer M, Disse B, Finnigan H, Kirsten A, Rodriguez-Roisin R, Tetzlaff K, Towse L, Wouters E, Magnussen H (2014) The impact of stepwise withdrawal of inhaled corticosteroids on lung function in COPD patients receiving dual bronchodilation: WISDOM study. Eur Respir J 44: Suppl. 58, 2423

116. Pedersen F, Lauer G, Quintini G, Holz O, Kirsten AM, Magnussen H, Rabe KF, Goldmann T, Watz H (2014) Multi-analyte profiling of inflammatory markers in COPD sputum. Eur Respir J 44: Suppl. 58, 837

117. Buhl R, Derom E, Ferguson G, Maltais F, Pizzichini E, Reid J, Watz H, Groenke L, Hamilton A, Tetzlaff K, Korducki L, Huisman H, Waitere-Wijker S, Bateman E (2014) Once-daily tiotropium and olodaterol fixed-dose combination via the respimat improves outcomes vs mono-components in COPD in two 1-year studies. Eur Respir J 44: Suppl. 58, 1895

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119. Maltais F, Iturri JBG, Kirsten A, Singh D, Hamilton A, Tetzlaff K, Zhao Y, Casaburi R (2014) Effects of 12 weeks of once-daily tiotropium and olodaterol fixed-dose combination on exercise endurance in patients with COPD. Eur Respir J 44 Supp 58: P283

120. Esser RW, Stoeckel MC, Kirsten A, Watz H, Lehmann K, Taube K, Magnussen H, Büchel C, von Leupoldt A (2014) Structural brain changes in patients with chronic obstructive pulmonary disease (COPD). Eur Respir J 44: Suppl. 58, 646

121. Mesquita R, Pitta F, Donaire-Gonzalez D, Deering BM, Patel M, Mitchell KE, Alison J, van Gestel AJR, Zogg S, Garcia-Aymerich J, Hill K, Romme E, Kon S, Albert P, Waschki B, Shrikrishna D, Singh SJ, Hopkinson NS, Miedinger D, Jenkins C, Polkey MI, Jenkins SC, Man WDC, Clarenbach CF, Hernandes NA, Hillman HR, Furlanetto KC, McKeough Z, Watts S, Cindy Ng, Brooks D, Eastwood PR, Sant'Anna T, Meijer K, Dürr S, Kohler M, Probst VS, Tal-Singer R, Leuppi JD, Calverley PMA, Smeenk W, Yates J, Costello RW, Goldstein R, Magnussen H, Wouters EFM, ZuWallack R, Watz H, Spruit MA (2014) Objective moderate-to-vigorous physical activity in 1064 patients with COPD after stratification for gender, FEV1 and BMI. Eur Respir J 44: Suppl. 58, 1981

122. Holz O, Roepcke S, Watz H, Lahu JM, Hohlfeld J (2014) Effect of exercise challenge on systemic inflammatory markers in healthy smokers and smokers with COPD. Eur Respir J 44: Suppl. 58, 4889